Sozinibercept for wet AMD, partnered with Carlyle
No capital raise or buyback data
Historical delivery and spending consistency. Data is limited for recently added companies.
Outcome quality (positive/negative readouts) reflects the science, not execution — shown above but excluded from the score.
These metrics reflect historical operational data only. They are not predictive of future performance, do not constitute investment advice, and should not be used as the basis for any investment decision.
Australian biotechs with < $20M aggregated turnover can claim a 43.5% refundable tax offseton eligible R&D expenditure each financial year (Jul–Jun). This is paid as a cash refund by the ATO — not a tax deduction — making it non-dilutive capital that directly extends cash runway.
Companies register eligible R&D activities with AusIndustry during the year, then lodge their tax return after 30 June. Refunds typically arrive October–Decemberof the same calendar year. For a company spending $5M/year on R&D, this is a ~$2.2M annual cash inflow.
Peer-reviewed papers & conference abstracts via PubMed
| Event | Type | Confidence | Impact | Date | Status |
|---|---|---|---|---|---|
| Sozinibercept Phase 3 wet AMD topline COAST pivotal trial topline results | data readout | Expected | arrow_upwardHigh | 30 June 2026 | Upcoming |
| OPT-302 LAM Development Program - 18-month staged program completionopen_in_new Opthea has an 18-month staged development program for OPT-302 funded by existing cash reserves with estimated expenditure of A$13.1 million over the program period. [Source: Reinstatement to ASX and Update on LAM Development Program, 2026-06-02] | other | Expected | arrow_upwardHigh | 2 Dec 2027 | Upcoming |
| Reinstatement to Official Quotationopen_in_new | other | Confirmed | removeMed | 2 June 2026 | Completed |
| Reinstatement to ASX and Update on LAM Development Programopen_in_new Opthea announces reinstatement to ASX trading following strategic review to focus on OPT-302 development for lymphangioleiomyomatosis (LAM), a rare pulmonary disease with unmet medical need. The company has an 18-month staged development program funded by existing cash reserves of A$31.2 million, with estimated expenditure of A$13.1 million over the program period. The company is also undertaking a name change to Ceryvyn Therapeutics Limited to reflect its strategic refocus. | other | Confirmed | removeMed | 2 June 2026 | Completed |
| Results posted — OPT-302 With Aflibercept in Neovascular Age-related Macular Degeneration (nAMD)open_in_new Results available at https://clinicaltrials.gov/study/NCT04757636 |
| data readout |
| Confirmed |
| arrow_upwardHigh |
| 13 Apr 2026 |
| Completed |
| Results posted — OPT-302 With Ranibizumab in Neovascular Age-related Macular Degeneration (nAMD)open_in_new Results available at https://clinicaltrials.gov/study/NCT04757610 | data readout | Confirmed | arrow_upwardHigh | 13 Apr 2026 | Completed |
| Results posted — A Dose Ranging Study of OPT-302 With Aflibercept for Persistent Diabetic Macularopen_in_new Results available at https://clinicaltrials.gov/study/NCT03397264 | data readout | Confirmed | arrow_upwardHigh | 13 Apr 2026 | Completed |
| Results posted — OPT-302 With Ranibizumab in Neovascular Age-related Macular Degeneration (nAMD)open_in_new Results available at https://clinicaltrials.gov/study/NCT04757610 | data readout | Confirmed | arrow_upwardHigh | 8 Apr 2026 | Completed |
| Results posted — A Dose Ranging Study of OPT-302 With Aflibercept for Persistent Diabetic Macularopen_in_new Results available at https://clinicaltrials.gov/study/NCT03397264 | data readout | Confirmed | arrow_upwardHigh | 8 Apr 2026 | Completed |
| Results posted — OPT-302 With Aflibercept in Neovascular Age-related Macular Degeneration (nAMD)open_in_new Results available at https://clinicaltrials.gov/study/NCT04757636 | data readout | Confirmed | arrow_upwardHigh | 8 Apr 2026 | Completed |
| Capital raise required Cash position improved from $28M to $86M in Q2 2025 (raise completed). Company CF positive by Q4 2025. | financing | Confirmed | removeMed | 30 June 2025 | Completed |