Developing Xolatryp for STEMI reperfusion injury (Phase 2) and NYR-BI03 for brain injury (Phase 1 completed). Dual cardiovascular + neuroprotection pipeline.
No capital raise or buyback data
Historical delivery and spending consistency. Data is limited for recently added companies.
Outcome quality (positive/negative readouts) reflects the science, not execution — shown above but excluded from the score.
These metrics reflect historical operational data only. They are not predictive of future performance, do not constitute investment advice, and should not be used as the basis for any investment decision.
These changes were automatically detected by comparing ClinicalTrials.gov records over time. A slipped date means the trial's expected completion moved later; pulled forward means it moved earlier.
| Event | Type | Confidence | Impact | Date | Status |
|---|---|---|---|---|---|
| PROTECT-MI Phase IIa first patient dosingopen_in_new First patient dosing in the PROTECT-MI Phase IIa trial expected in April 2026. [Source: Nyrada PROTECT-MI Phase IIa Trial To Commence, 2026-03-18] | commercial milestone | Expected | arrow_upwardHigh | 30 Apr 2026 | Overdue |
| NYR-BI03 Phase 1 brain injury final results Phase 1 FIH completed 2025, all 3 cohorts cleared by Safety Review Committee | data readout | Expected | removeMed | 30 June 2026 | Upcoming |
| Xolatryp Phase 2a primary completion (Day 30 safety) Primary endpoint: incidence of AEs/SAEs at Day 30. Secondary: troponin AUC, ST-segment resolution | data readout | Confirmed | arrow_upwardHigh | 30 Apr 2027 | Upcoming |
| Xolatryp USPTO — Nyrada Receives Notice of Allowance for Xolatryp US Patentopen_in_new Nyrada received a Notice of Allowance from the United States Patent and Trademark Office for a composition of matter patent covering Xolatryp's chemical structure. The granted patent will provide 20-year IP protection within the United States against unauthorised manufacture, use, sale, or import of Xolatryp. | regulatory decision | Confirmed | removeMed | 19 May 2026 | Completed |
| Pause in Tradingopen_in_new Trading in NYR securities has been temporarily paused pending a further announcement. The pause indicates an imminent material disclosure or corporate action requiring market suspension. | other | Confirmed | Med |
| 19 May 2026 |
| Completed |
| First Site Activated in Nyradas PROTECT-MI Phase IIa Trialopen_in_new This announcement reports the activation of the first clinical trial site (Nepean Hospital, NSW) for the PROTECT-MI Phase IIa trial, marking the formal launch of recruitment operations. No efficacy or outcome results are available as the trial has only just begun enrolling patients. The prior Phase I trial (48 participants) met its primary endpoint, confirming Xolatryp was safe and well-tolerated at all doses tested. | data readout | Confirmed | removeMed | 22 Apr 2026 | Completed |
| PROTECT-MI Phase IIa site initiation visitsopen_in_new | commercial milestone | Confirmed | removeMed | 31 Mar 2026(1× delayed) | Completed |
| Xolatryp Phase 2a PROTECT-MI first patient dosedopen_in_new The PROTECT-MI Phase IIa trial has not yet commenced; this announcement confirms site initiation visits are on track for March 2026 with first patient dosing expected in April 2026. Seven hospitals across Australia have been selected as initial trial sites. No efficacy or safety results are available as the trial has not yet enrolled patients. | data readout | Confirmed | arrow_upwardHigh | 18 Mar 2026 | Completed |