Trofinetide for Rett syndrome, partnered with Acadia
Historical delivery and spending consistency. Data is limited for recently added companies.
Outcome quality (positive/negative readouts) reflects the science, not execution — shown above but excluded from the score.
These metrics reflect historical operational data only. They are not predictive of future performance, do not constitute investment advice, and should not be used as the basis for any investment decision.
Peer-reviewed papers & conference abstracts via PubMed
| Event | Type | Confidence | Impact | Date | Status |
|---|---|---|---|---|---|
| NNZ-2591 Phase 2 Phelan-McDermid interim Interim efficacy data in rare paediatric neurological condition | data readout | Expected | arrow_upwardHigh | 31 July 2026 | Upcoming |
| PHASE3 data readout — A Study of NNZ-2591 in Pediatric Participants With Phelan-McDermid Syndromeopen_in_new Primary completion expected for NCT07281079. Indication: {"Phelan-McDermid Syndrome"} | data readout | Speculative | removeMed | 31 Oct 2027 | Upcoming |
| Update - Notification of buy-back - NEUopen_in_new | financing | Confirmed | removeMed | 13 May 2026 | Completed |
| Update - Notification of buy-back - NEUopen_in_new | financing | Confirmed | removeMed | 11 May 2026 | Completed |
| Update - Notification of buy-back - NEUopen_in_new | financing |
| removeMed |
| 10 May 2026 |
| Completed |
| DAYBUE royalty payment Quarterly update filed (auto-resolved) | commercial milestone | Confirmed | removeMed | 6 May 2026 | Completed |
| Update - Notification of buy-back - NEUopen_in_new | financing | Confirmed | removeMed | 6 May 2026 | Completed |
| Results posted — An Open-Label Study of Oral NNZ-2591 in Phelan-McDermid Syndrome (PMS-001)open_in_new Results available at https://clinicaltrials.gov/study/NCT05025241 | data readout | Confirmed | arrow_upwardHigh | 13 Apr 2026 | Completed |
| Results posted — An Open-Label Study of Oral NNZ-2591 in Pitt Hopkins Syndrome (PTHS-001)open_in_new Results available at https://clinicaltrials.gov/study/NCT05025332 | data readout | Confirmed | arrow_upwardHigh | 13 Apr 2026 | Completed |
| Results posted — An Open-Label Study of Oral NNZ-2591 in Pitt Hopkins Syndrome (PTHS-001)open_in_new Results available at https://clinicaltrials.gov/study/NCT05025332 | data readout | Confirmed | arrow_upwardHigh | 8 Apr 2026 | Completed |
| Results posted — An Open-Label Study of Oral NNZ-2591 in Phelan-McDermid Syndrome (PMS-001)open_in_new Results available at https://clinicaltrials.gov/study/NCT05025241 | data readout | Confirmed | arrow_upwardHigh | 8 Apr 2026 | Completed |