DMX-200 (atrasentan + irbesartan) in Phase 3 for focal segmental glomerulosclerosis (FSGS)
No capital raise or buyback data
Historical delivery and spending consistency — data is limited for recently added companies.
Outcome quality (positive/negative readouts) reflects the science, not execution — shown above but excluded from the score.
These metrics reflect historical operational data only. They are not predictive of future performance, do not constitute investment advice, and should not be used as the basis for any investment decision.
No cash flow data
| Event | Type | Confidence | Impact | Date | Status |
|---|---|---|---|---|---|
| ACTION3 Blinded Statistical Assumptions Review — Results Due April 2026open_in_new Dimerix conducting a blinded review of ACTION3 Phase 3 statistical assumptions (primary endpoint: % reduction in proteinuria vs placebo). Review uses methods prespecified in the Statistical Analysis Plan submitted to the FDA. The blinded review is independent and maintains study integrity. Results expected April 2026. Confirms trial is powered to detect treatment effect. Previously passed 7 IDMC reviews with no safety concerns and a March 2024 futility analysis. | data readout | Confirmed | arrow_upwardHigh | 30 Apr 2026 | Upcoming |
| ACTION3 Phase 3 Trial Full Study Completionopen_in_new The full 2-year ACTION3 Phase 3 study is expected to complete in March 2028, with final efficacy results pending. [Source: Dimerix Phase 3 Trial Last Patient Receives First Dose, 2026-03-09] | data readout | Expected | arrow_upwardHigh | 31 Mar 2028 | Upcoming |
| PHASE3 data readout — A Study of the Efficacy and Safety of DMX-200 in Patients With FSGS Who Are Receopen_in_new Primary completion expected for NCT05183646. Indication: {FSGS} | data readout | Speculative | removeMed | 1 Dec 2029 | Upcoming |
| Dimerix Phase 3 Trial Last Patient Receives First Doseopen_in_new The ACTION3 Phase 3 trial has completed recruitment with 333 adult patients randomised and dosed, exceeding the target of 286 patients, with the full 2-year treatment period expected to conclude in March 2028. A pre-specified interim analysis from March 2024 showed DMX-200 was performing better than placebo in reducing proteinuria in the first 72 randomised patients. The trial has passed seven scheduled Independent Data Monitoring Committee reviews with no protocol changes or safety concerns ide | data readout | Confirmed | removeMed | 9 Mar 2026 | Completed |
| Dimerix Phase 3 Trial Last Patient Receives First Doseopen_in_new The ACTION3 Phase 3 trial has completed recruitment with 333 adult patients randomised and dosed, exceeding the target of 286 patients. A pre-specified interim analysis in March 2024 of the first 72 randomised patients showed DMX-200 was performing better than placebo in reducing proteinuria. The full 2-year study is expected to complete in March 2028, with final efficacy results pending. |
| data readout |
| Confirmed |
| removeMed |
| 9 Mar 2026 |
| Completed |