Xanamem for Alzheimers disease via cortisol modulation
Australian biotechs with < $20M aggregated turnover can claim a 43.5% refundable tax offseton eligible R&D expenditure each financial year (Jul–Jun). This is paid as a cash refund by the ATO — not a tax deduction — making it non-dilutive capital that directly extends cash runway.
Companies register eligible R&D activities with AusIndustry during the year, then lodge their tax return after 30 June. Refunds typically arrive October–Decemberof the same calendar year. For a company spending $5M/year on R&D, this is a ~$2.2M annual cash inflow.
Peer-reviewed papers & conference abstracts via PubMed
Historical delivery and spending consistency — data is limited for recently added companies.
Outcome quality (positive/negative readouts) reflects the science, not execution — shown above but excluded from the score.
These metrics reflect historical operational data only. They are not predictive of future performance, do not constitute investment advice, and should not be used as the basis for any investment decision.
These changes were automatically detected by comparing ClinicalTrials.gov records over time. A slipped date means the trial's expected completion moved later; pulled forward means it moved earlier.
| Event | Type | Confidence | Impact | Date | Status |
|---|---|---|---|---|---|
| Xanamem Phase 2 XanaMIA study data Phase 2 data in mild-moderate Alzheimer disease via cortisol modulation | data readout | Expected | arrow_upwardHigh | 30 June 2026 | Upcoming |
| PHASE2/PHASE3 data readout — Effect of 10 mg Xanamem on Dementia Due to Alzheimer's Diseaseopen_in_new Primary completion expected for NCT06125951. Indication: {"Dementia Moderate","Dementia, Mild","Alzheimer Disease"} | data readout | Speculative | removeMed | 1 Oct 2026 | Upcoming |
| Results posted — A Phase II Study to Assess the Safety, Tolerability and Efficacy of Xanamem™ in open_in_new Results available at https://clinicaltrials.gov/study/NCT02727699 | data readout | Confirmed | arrow_upwardHigh | 8 Apr 2026 | Completed |
| Results posted — A Phase II Study to Assess the Safety, Tolerability and Efficacy of Xanamem™ in open_in_new Results available at https://clinicaltrials.gov/study/NCT02727699 | data readout | Confirmed | arrow_upwardHigh | 13 Apr 2026 | Completed |