Senolytic and anti-inflammatory oncology pipeline
Historical delivery and spending consistency. Data is limited for recently added companies.
Outcome quality (positive/negative readouts) reflects the science, not execution — shown above but excluded from the score.
These metrics reflect historical operational data only. They are not predictive of future performance, do not constitute investment advice, and should not be used as the basis for any investment decision.
Australian biotechs with < $20M aggregated turnover can claim a 43.5% refundable tax offseton eligible R&D expenditure each financial year (Jul–Jun). This is paid as a cash refund by the ATO — not a tax deduction — making it non-dilutive capital that directly extends cash runway.
Companies register eligible R&D activities with AusIndustry during the year, then lodge their tax return after 30 June. Refunds typically arrive October–Decemberof the same calendar year. For a company spending $5M/year on R&D, this is a ~$2.2M annual cash inflow.
| Event | Type | Confidence | Impact | Date | Status |
|---|
| SOF-SKN manufacturing begins to ensure clinical trial readiopen_in_new Noxopharm has commenced manufacturing of SOF-SKN for a planned clinical trial later in 2026, with the process expected to take several weeks including quality control checks. The company is investigating prospects for a pilot study in cutaneous lupus erythematosus (CLE), a chronic autoimmune inflammatory disease with a global market worth over US$3.3 billion. | other | Confirmed | removeMed | 8 June 2026 | Completed |
| New data confirms cancer-fighting potentialopen_in_new Noxopharm has demonstrated that its Sofra technology platform can significantly amplify TLR8 immune activation for cancer treatment, with oligonucleotides showing >200-fold enhancement in human skin biopsies and ~3-fold increases in animal models. The company is advancing development toward humanized mouse and cancer model testing, positioning the platform as a potential competitive addition to the immuno-oncology market projected to reach US$185 billion by 2035. | other | Confirmed | removeMed | 25 May 2026 | Completed |
| Proposed issue of securities - NOXopen_in_new | financing | Confirmed | removeMed | 7 May 2026 | Completed |
| SOF-SKN™ FDA — Noxopharm progresses US regulatory strategyopen_in_new Noxopharm is preparing for a pre-IND meeting with the US FDA for SOF-SKN™, a drug candidate for chronic inflammation caused by cutaneous lupus erythematosus, having engaged CRO Novotech to support the data package preparation. This pre-IND meeting is a precursor step toward a full IND application submission in the US. | regulatory decision | Confirmed | removeMed | 5 May 2026 | Completed |
| Results posted — Safety and Tolerability of NOX66 in Combination With Palliative Radiotherapy in open_in_new Results available at https://clinicaltrials.gov/study/NCT03307629 | data readout | Confirmed | arrow_upwardHigh | 13 Apr 2026 | Completed |
| Results posted — Safety, PK and Efficacy of NOX66 as a Monotherapy and Combined With Carboplatin open_in_new Results available at https://clinicaltrials.gov/study/NCT02941523 | data readout | Confirmed | arrow_upwardHigh | 13 Apr 2026 | Completed |
| Results posted — A Study of NOX66 and External Beam Radiotherapy in Patients With Metastatic Castopen_in_new Results available at https://clinicaltrials.gov/study/NCT04957290 | data readout | Confirmed | arrow_upwardHigh | 13 Apr 2026 | Completed |
| Results posted — A Study of NOX66 Plus Doxorubicin in Anthracycline-naïve, Adult Patients With Soopen_in_new Results available at https://clinicaltrials.gov/study/NCT05100628 | data readout | Confirmed | arrow_upwardHigh | 13 Apr 2026 | Completed |
| Results posted — A Study of NOX66 Plus Doxorubicin in Anthracycline-naïve, Adult Patients With Soopen_in_new Results available at https://clinicaltrials.gov/study/NCT05100628 | data readout | Confirmed | arrow_upwardHigh | 8 Apr 2026 | Completed |
| Results posted — A Study of NOX66 and External Beam Radiotherapy in Patients With Metastatic Castopen_in_new Results available at https://clinicaltrials.gov/study/NCT04957290 | data readout | Confirmed | arrow_upwardHigh | 8 Apr 2026 | Completed |
| Results posted — Safety and Tolerability of NOX66 in Combination With Palliative Radiotherapy in open_in_new Results available at https://clinicaltrials.gov/study/NCT03307629 | data readout | Confirmed | arrow_upwardHigh | 8 Apr 2026 | Completed |
| Results posted — Safety, PK and Efficacy of NOX66 as a Monotherapy and Combined With Carboplatin open_in_new Results available at https://clinicaltrials.gov/study/NCT02941523 | data readout | Confirmed | arrow_upwardHigh | 8 Apr 2026 | Completed |