Topical drug delivery technology, LENZETTO hormone therapy
Historical delivery and spending consistency. Data is limited for recently added companies.
Outcome quality (positive/negative readouts) reflects the science, not execution — shown above but excluded from the score.
These metrics reflect historical operational data only. They are not predictive of future performance, do not constitute investment advice, and should not be used as the basis for any investment decision.
Australian biotechs with < $20M aggregated turnover can claim a 43.5% refundable tax offseton eligible R&D expenditure each financial year (Jul–Jun). This is paid as a cash refund by the ATO — not a tax deduction — making it non-dilutive capital that directly extends cash runway.
Companies register eligible R&D activities with AusIndustry during the year, then lodge their tax return after 30 June. Refunds typically arrive October–Decemberof the same calendar year. For a company spending $5M/year on R&D, this is a ~$2.2M annual cash inflow.
Peer-reviewed papers & conference abstracts via PubMed
| Event | Type | Confidence | Impact | Date | Status |
|---|---|---|---|---|---|
| Dapsone 7.5% Gel US launch revenue FDA approved Aug 2024, launched May 2025 via TruPharma. US market >US$37.4M annually | commercial milestone | Confirmed | removeMed | 30 June 2026 | Upcoming |
| Acyclovir Cream 5% FDA decision ANDA accepted for review since Aug 2022. Cold sore treatment. US market >US$29M | regulatory decision | Expected | removeMed | 31 Dec 2026 | Upcoming |
| Lenzetto milestone payments over two years from launchopen_in_new Acrux licensed Lenzetto to Gedeon Richter Plc for the Australian market with total milestone payments of up to AUD 5.4 million, including upfront signing, TGA regulatory approval, and commercial sales milestones. The licensing deal has been executed, triggering the initial milestone structure. | commercial milestone | Expected | removeMed | 29 May 2026 | Completed |
| Acrux licenses Lenzetto for Australian market for AUD5.4mopen_in_new Acrux has amended its licensing agreement with Gedeon Richter for Lenzetto® (transdermal Estradiol spray) to include Australian market rights, with potential milestone payments totaling up to AUD 5.4 million over two years from product launch. The product addresses a critical shortage of Menopause Hormone Therapy products in Australia and leverages Acrux's Patchless Patch™ technology, which is already generating EUR 50 million in global sales. | other | Confirmed | removeMed | 27 May 2026 | Completed |
| N/A N/A — Capital Gains Tax exemptions remain in place for Acruxopen_in_new This announcement relates to Capital Gains Tax exemptions for Acrux as a Pooled Development Fund, not a regulatory milestone. There is no drug approval, designation, or regulatory body involved. | regulatory decision | Confirmed | removeMed | 13 May 2026 | Completed |
| Acrux raises $1.6 million via Share Placementopen_in_new | financing | Confirmed | removeMed | 11 May 2026 | Completed |
| Proposed issue of securities - ACRopen_in_new | financing | Confirmed | removeMed | 11 May 2026 | Completed |
| Female Testosterone (Metered Dose Transdermal System) FDA — Acrux strategy focuses on Female Testosterone for low libidoopen_in_new Acrux received FDA feedback on completed Phase I and II clinical trials for its Female Testosterone transdermal product, with the FDA providing a viable pathway to proceed to Phase III development. The company is now pursuing a co-development strategy to bring the product to market for HSDD, an area of high unmet need with no currently approved female testosterone treatment in the US. | regulatory decision | Confirmed | removeMed | 27 Apr 2026 | Completed |